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Two-carbon nitrogen ring bases (adenine and guanine) covalently linked to a sugar (ribose or deoxyribose) and one to three phosphate groups; can function as extracellular messengers, antimetabolites, and chain terminators that inhibit viral DNA polymerase.
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Acyclovir triphosphate sodium (AcycloGTP sodium) is a derivative of Acyclovir that functions as an inhibitor of viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate (dGTP). This compound is also recognized as an inhibitor of HIV-1 reverse transcriptase, ultimately leading to the termination of viral DNA synthesis. It is intended for research use only.
Competitively inhibits viral DNA polymerase.
Acts as an analog to deoxyguanosine triphosphate (dGTP).
Inhibits HIV-1 reverse transcriptase.
Causes termination of viral DNA synthesis.
Available for research purposes.
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Adenosine receptor antagonist 3 is a potent antagonist of adenosine receptor. It has potential for the research of cancer disease, as extracted from patent WO2019233994A1, compound 1. It is for research use only.
Potent antagonist of adenosine receptor
Potential for cancer disease research
For research use only
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Adenosine 2',5'-diphosphate sodium is a potent competitive antagonist of the P2Y1 receptor, and also exhibits non-selective antagonism at recombinant and human platelet P2X1 receptors. This endogenous metabolite is supplied as a white to off-white solid with 99.0% purity.
Key Features & Applications:
Competitive P2Y1 antagonist
Non-selective P2X1 receptor antagonism in platelets
Research use only
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2 -O-Methyl-ATP is a chemically modified derivative of ATP in which the hydroxyl group at the ribose 2 position is replaced with a methyl group This ribose modification confers resistance to nuclease-mediated degradation thereby increasing its biological stability The modified nucleotide is commonly employed in biomedical research to investigate RNA structure-function relationships and RNA modification pathways and to study interactions influencing RNA polymerase specificity and catalytic activity Additionally 2 -O-Methyl-ATP serves as a tool in probe design for RNA interference experiments and aids in elucidating intracellular metabolic pathways involving nucleotide analogs
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2-Amino-ATP is a modified nucleotide structurally related to ATP (adenosine triphosphate) featuring an amino substitution at the adenine ring s 2-position It acts as an ATP analog capable of competitively binding at the active sites of ATP-dependent enzymes potentially modulating their enzymatic activity and influencing downstream signaling pathways In research settings 2-Amino-ATP serves as a molecular tool to examine substrate specificity mechanistic aspects of ATP-binding enzymes (e g kinases and ATPases) and nucleotide-dependent receptor interactions facilitating studies of nucleotide signaling and cellular metabolism
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BRM/BRG1 ATP Inhibitor-2 is a BRG1/BRM ATPase inhibitor used for the research of BAF-related disorders. It is intended for research use only and is not sold to patients. The compound has a molecular weight of 412.53 and appears as a white to off-white solid. It is soluble in DMSO at 100 mg/mL.
Used for the research of BAF-related disorders
Appears as a white to off-white solid
Soluble in DMSO at 100 mg/mL
Stock solutions can be stored at -80°C for 6 months or -20°C for 1 month
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Coenzyme A trilithium salt | Purity: ≥85% | Mol Wt: 767.5 | CAS No: 93-18-4-3 | Biochemical cofactor involved in metabolic pathways and energy production via acyl transfer and thioesterification | 10mg
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MW 392.15 Da, Purity >95%. Potent, specific adenosine kinase inhibitor (IC₅₀ = 26 nM). Inhibits platelet aggregation and spreading, and interferes with adenosine and adenine nucleotide metabolism. Additionally inhibits other kinases such as ERK2 (Ki = 525 nM).
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Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist. It exhibits anti-tumor activity by inhibiting tumor growth in vivo. This compound is characterized by its potent inhibitory concentrations for both A2a and A2b adenosine receptors.
Orally active A2a/A2b adenosine receptor antagonist
IC50 of 1 nM for A2a adenosine receptor
IC50 of 3 nM for A2b adenosine receptor
Exhibits anti-tumor activity
Inhibits tumor growth in female C57BL/6 mice
Demonstrates specific pharmacokinetic profiles in mice studies
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Adenosine antagonist-1 acts as an adenosine A3 receptor (AA3R) antagonist. purity: 99%
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